CYDECTIN POUR-ON, FOR BEEF AND DAIRY CATTLE, MOXIDECTIN, ELANCO

Product Description

Pour-On for Beef and Dairy Cattle Moxidectin, Antiparasitic
Contains 5 mg moxidectin/mL
For Treatment of Infections and Infestations Due to Internal and External Parasites of Beef and Dairy Cattle
Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. If animals are likely to be reinfected following treatment, a strategic parasite control program should be established.
Mode of Action: Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. CYDECTIN (moxidectin) Pour-On is specially formulated to allow moxidectin to be absorbed through the skin and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. Moxidectin binds selectively and with high affinity to glutamate-gated chloride ion channels which are critical to the function of invertebrate nerve and muscle cells. This interferes with neurotransmission resulting in paralysis and elimination of the parasite.
Indications: CYDECTIN Pour-On when applied at the recommended dose level of 0.5 mg/2.2 lb (0.5 mg/kg) body weight is effective in the treatment and control of the following internal [adult and fourth-stage larvae (L4)] and external parasites of cattle:
Gastrointestinal Roundworms
Ostertagia ostertagi - Adult and L4 (including inhibited larvae); Haemonchus placei - Adult and L; Trichostrongylus axei - Adult and L; Trichostrongylus colubriformis - Adult and L; Cooperia oncophora - Adult and L; Cooperia pectinata Adult: Cooperia punctata - Adult and L; Cooperia spatulata ? Adult; Cooperia surnabada - Adult and L; Bunostomum phlebotomum Adult; Nematodirus helvetianus - Adult and L; Oesophagostomum radiatum - Adult and L; Lungworms ; Dictyocaulus viviparus - Adult and L; Cattle Grubs ; Hypoderma bovis; Hypoderma lineatum Mites Chorioptes bovis; Psoroptes ovis (Psoroptes communis var. bovis) Lice Linognathus vituli; Haematopinus eurysternus; Solenopotes capillatus; Bovicola (Damalinia) bovi Horn Flies Haematobia irritans

Management Considerations for External Parasites: For most effective external parasite control, CYDECTIN Pour-On should be applied to all cattle in the herd. Cattle entering the herd following this administration should be treated prior to introduction. Consult your veterinarian or a livestock entomologist for the most appropriate time to apply CYDECTIN Pour-On in your location to effectively control horn flies and external parasites. CYDECTIN Pour-On provides seven days of persistent activity against horn flies. For optimal control of horn flies, the product should be used as part of an integrated control program utilizing other methods to provide extended control.
Persistent Activity: CYDECTIN Pour-On has been proven to effectively control infections and protect from reinfection with Haemonchus placei for 14 days after treatment, Oesophagostomum radiatum and Ostertagia ostertagi for 28 days after treatment, and Dictyocaulus viviparus for 42 days after treatment. Efficacy below 90% was observed in some Ostertagia ostertagi persistent activity studies at 21 and 28 days posttreatment.
Dosage: CYDECTIN (moxidectin) Pour-On is a ready-to-use topical formulation intended for direct application to the hair and skin in a narrow strip extending along the top of the back from the withers to the tailhead (see Figure 1). Due to the angular topline characteristic of most dairy breeds, it is recommended that all pour-on products be applied slowly to dairy cows. Apply to healthy skin avoiding any mange scabs, skin lesions, mud or manure. Treated cattle can be easily recognized by the characteristic purple color, which will remain for a short period of time after treatment. The recommended rate of administration is 1 mL for each 22 lb (10 kg) body weight which provides 0.5 mg moxidectin for each 2.2 lb (0.5 mg/kg) body weight. The table below will assist in the calculation of the appropriate volume of pour-on which must be applied based on the weight of animal being treated.
Body Weight Lb (kg) Dose ml Body WeightLb (kg) DosemL
88 (40) 4 330 (150) 15
110 (50) 5 440 (200) 20
132 (60) 6 550 (250) 25
154 (70) 7 660 (300) 30
176 (80) 8 770 (350) 35
198 (90) 9 880 (400) 40
220 (100) 10 990 (450) 45
242 (110) 11 1100 (500) 50
264 (120) 12 1210 (550) 55
286 (130) 13 1320 (600) 60
308 (140) 14 1430 (650) 69

***Not for sale in California